| Date | Shareholder name | Reason of Disclosure | Buy/Sell and Involved Shares |
Average Price per share | Current Holdings | % of Issued Shares |
| 11/06/2026 | Crescent Capital Investments Ltd. | 1001(L) | +322,278,770(L) | 322,278,770(L) | 23.26 | |
| 11/06/2026 | PharmaTech Holdings II Ltd. | 1001(L) | +126,151,645(L) | 126,151,645(L) | 9.11 | |
| 11/06/2026 | Rojanavanichkul Danai | 1704(L) | -264,582,255(L) | 0(L) | 0.00 | |
| 11/06/2026 | Veneto Holdings Ltd. | 1704(L) | -264,582,255(L) | 0(L) | 0.00 | |
| 11/06/2026 | Ares Holdings L.P. | 1001(L) | +437,443,815(L) | 437,443,815(L) | 31.57 | |
| 11/06/2026 | Ares Management Corporation | 1001(L) | +437,443,815(L) | 437,443,815(L) | 31.57 | |
| 11/06/2026 | Ares Partners Holdco LLC | 1001(L) | +437,443,815(L) | 437,443,815(L) | 31.57 | |
| 11/06/2026 | Crescent ACSO Institutional Holdings I Pte. Ltd. | 1001(L) | +115,165,045(L) | 115,165,045(L) | 8.31 | |
| 11/06/2026 | Tech-Med Holdings III Ltd. | 1001(L) | +138,430,610(L) | 138,430,610(L) | 9.99 | |
| 11/06/2026 | PharmaTech Investments II Ltd. | 1001(L) | +126,151,645(L) | 126,151,645(L) | 9.11 | |
| 11/06/2026 | Crescent ACSO Investment Management Ltd | 1704(L) | -115,165,045(L) | 0(L) | 0.00 | |
| 11/06/2026 | HAND David McKee | 1711(L) | -437,443,815(L) | 0(L) | 0.00 | |
| 11/06/2026 | Ressler Antony Peter | 1001(L) | +437,443,815(L) | 437,443,815(L) | 31.57 | |
| 11/06/2026 | Ares Management Asia Holdings, L.P. | 1001(L) | +437,443,815(L) | 437,443,815(L) | 31.57 | |
| 11/06/2026 | Crescent Institutional Investment Management Ltd. | 1001(L) | +115,165,045(L) | 115,165,045(L) | 8.31 | |
| 10/06/2026 | ZHOU Feng | 1201(L) | -50,000,000(L) | 619,873,932(L) | 44.74 | |
| 10/06/2026 | XIE Fangmin | 1213(L) | -84,430,610(L) | 535,443,322(L) | 38.65 | |
| 10/06/2026 | ZHOU Feng | 1213(L) | -84,430,610(L) | 535,443,322(L) | 38.65 | |
| 10/06/2026 | XIE Fangmin | 1201(L) | -50,000,000(L) | 619,873,932(L) | 44.74 | |
| 10/06/2026 | Celaeno Group Limited | 1201(L) | -50,000,000(L) | 136,158,297(L) | 9.83 | |
| 10/06/2026 | Crescent China Investment Management Ltd. | 1704(L) | -437,443,815(L) | 0(L) | 0.00 | |
| 02/02/2026 | XIE Fangmin | 1111(L) | +45,181,000(L) | 669,873,932(L) | 48.35 | |
| 02/02/2026 | HAND David McKee | 1210(L) | 437,443,815(L) | 31.57 | ||
| 02/02/2026 | Tech-Med Cayman III Ltd. | 1210(L) | 138,430,610(L) | 9.99 | ||
| 02/02/2026 | Fangrong Management Limited | 1210(L) | 246,538,362(L) | 17.79 | ||
| 02/02/2026 | Tech-Med Investments (S) Pte. Ltd. | 1210(L) | 138,430,610(L) | 9.99 | ||
| 02/02/2026 | ZOU Yuming | 1210(L) | 13,500,000(L) | 0.97 | ||
| 02/02/2026 | Crescent China Investment Management Ltd. | 1210(L) | 437,443,815(L) | 31.57 | ||
| 02/02/2026 | ZHOU Feng | 1111(L) | +45,181,000(L) | 669,873,932(L) | 48.35 | |
| 29/01/2026 | ZHOU Feng | 1209(L) | -45,181,000(L) | 624,692,932(L) | 46.61 | |
| 29/01/2026 | XIE Fangmin | 1209(L) | -45,181,000(L) | 624,692,932(L) | 46.61 | |
| 16/01/2026 | ZHOU Feng | 1213(L) | -41,575,898(L) | 669,873,932(L) | 49.98 | |
| 16/01/2026 | XIE Fangmin | 1213(L) | -41,575,898(L) | 669,873,932(L) | 49.98 | |
| 31/12/2025 | ZOU Yuming | 1201(L) | -5,000,000(L) | HKD2.310(L) | 13,500,000(L) | 1.01 |
| 31/10/2025 | ZHOU Feng | 1201(L) | -3,000,000(L) | 711,449,830(L) | 53.08 | |
| 31/10/2025 | XIE Fangmin | 1201(L) | -3,000,000(L) | 711,449,830(L) | 53.08 | |
| 27/10/2025 | ZHOU Feng | 1213(L) | -27,019,097(L) | 714,449,830(L) | 53.31 | |
| 27/10/2025 | XIE Fangmin | 1213(L) | -27,019,097(L) | 714,449,830(L) | 53.31 | |
| 30/09/2025 | ZOU Yuming | 1201(L) | -5,000,000(L) | HKD4.270(L) | 18,500,000(L) | 1.38 |
| 08/09/2025 | Vistra Trust (Hong Kong) Limited | 1213(L) | -41,575,898(L) | 48,280,903(L) | 3.60 | |
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| Remark: | (L) - Long Position, (S) - Short Position, (P) Lending; |
| Real time quote last updated: 22/06/2026 18:00 | |
| Real-time basic market prices of Hong Kong securities are provided by HKEx; a Designated Website authorized by the HKEx Group to provide the Service | |